Significance of the focal brain lesion in development of vestibular and acoustical disturbances in patients with multiple sclerosis

Abstract

We have examined 72 patients aged from 18 till 62 with cerebral and cerebrospinal multiple sclerosis (MS) form. All patients have been underwent оtoneurologiс examination, electronystagmography (ENG), caloric tests, pure-tone audiometry, high frequency audiometry up to 20 kHz, impedance audiometry, auditory brainstem responses (ABR), magnetic resonance imaging (MRI). 59 patients had pathologically changed in MRI demyelination lesion in the brainstem. Demyelinization of the brainstem affects acoustical and vestibular function in patients with multiple sclerosis. Pathological changes of pure-tone audiometry, high frequency audiometry, acoustic reflexes and ABR may be regarded as subclinical signs of demyelinization of the cochleovestibular analyzer.

Keywords

• рассеянный склероз
• магниторезонансная томография головного мозга (МРТ)
• расширенное отоневрологическое обследование
• оtoneurologiсal investigation