Recent developments in the asymmetric Reformatsky-type reaction

Abstract

This review collects the most important developments in asymmetric Reformatsky-type reactions published since the beginning of 2013, including both diastereoselective methodologies based on the use of chiral substrates and enantioselective catalytic procedures.

Keywords

• asymmetric (aza)-Reformatsky reaction
• asymmetric synthesis
• chirality
• diastereoselectivity
• enantioselectivity
• total synthesis