P478: THE GERMLINE VARIANT GFI1-36N PROMOTES GENETIC INSTABILITY IN LEUKEMIC CELLS AND OPENS NEW THERAPEUTIC APPROACHES FOR ABOUT 15% OF ALL AML PATIENTS
J. Vorwerk,
D. Frank,
K. Sun,
F. Neumannn,
M. Heuser,
D. Kunadt,
W. E. Berdel,
J.-H. Mikesch,
C. Schliemann,
G. Lenz,
A. K. Jayavelu,
C. Khandanpour
Affiliations
J. Vorwerk
1 Department of Medicine A, University Hospital Münster
D. Frank
1 Department of Medicine A, University Hospital Münster
K. Sun
1 Department of Medicine A, University Hospital Münster
F. Neumannn
2 Fluorescence Microscopy Facility Münster, Institute of Medical Physics and Biophysics, University of Münster, Münster
M. Heuser
3 Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover
D. Kunadt
4 Department of Internal Medicine I, University Hospital Dresden, Dresden
W. E. Berdel
1 Department of Medicine A, University Hospital Münster
J.-H. Mikesch
1 Department of Medicine A, University Hospital Münster
C. Schliemann
1 Department of Medicine A, University Hospital Münster
G. Lenz
1 Department of Medicine A, University Hospital Münster
A. K. Jayavelu
5 Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Munich
C. Khandanpour
1 Department of Medicine A, University Hospital Münster