Nitrous Oxide Toxicity with Methylenetetrahydrofolate Reductase Deficiency

Abstract

The neurological deterioration and death of a child with methylenetetrahydrofolate reductase (MTHFR) deficiency following anesthetization with nitrous oxide are reported from the University of Wisconsin Medical School, Madison, WI, and McGill University, Montreal.

Keywords

• methylenetetrahydrofolate reductase deficiency
• nitrous oxide anesthesias
• infantile fibrosarcoma