Current and Perspective Sensing Methods for Monkeypox Virus

Ijaz Gul; Changyue Liu; Xi Yuan; Zhicheng Du; Shiyao Zhai; Zhengyang Lei; Qun Chen; Muhammad Akmal Raheem; Qian He; Qiuyue Hu; Chufan Xiao; Zhang Haihui; Runming Wang; Sanyang Han; Ke Du; Dongmei Yu; Can Yang Zhang; Peiwu Qin

doi:10.3390/bioengineering9100571

Bioengineering (Oct 2022)

Current and Perspective Sensing Methods for Monkeypox Virus

Ijaz Gul,
Changyue Liu,
Xi Yuan,
Zhicheng Du,
Shiyao Zhai,
Zhengyang Lei,
Qun Chen,
Muhammad Akmal Raheem,
Qian He,
Qiuyue Hu,
Chufan Xiao,
Zhang Haihui,
Runming Wang,
Sanyang Han,
Ke Du,
Dongmei Yu,
Can Yang Zhang,
Peiwu Qin

Affiliations

Ijaz Gul: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Changyue Liu: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Xi Yuan: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Zhicheng Du: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Shiyao Zhai: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Zhengyang Lei: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Qun Chen: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Muhammad Akmal Raheem: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Qian He: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Qiuyue Hu: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Chufan Xiao: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Zhang Haihui: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Runming Wang: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Sanyang Han: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Ke Du: Chemical and Environmental Engineering, University of California, Riverside, CA 92521, USA
Dongmei Yu: School of Mechanical, Electrical & Information Engineering, Shandong University, Weihai 264209, China
Can Yang Zhang: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China
Peiwu Qin: Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China

DOI: https://doi.org/10.3390/bioengineering9100571
Journal volume & issue: Vol. 9, no. 10
p. 571

Abstract

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The outbreak of the monkeypox virus (MPXV) in non-endemic countries is an emerging global health threat and may have an economic impact if proactive actions are not taken. As shown by the COVID-19 pandemic, rapid, accurate, and cost-effective virus detection techniques play a pivotal role in disease diagnosis and control. Considering the sudden multicountry MPXV outbreak, a critical evaluation of the MPXV detection approaches would be a timely addition to the endeavors in progress for MPXV control and prevention. Herein, we evaluate the current MPXV detection methods, discuss their pros and cons, and provide recommended solutions to the problems. We review the traditional and emerging nucleic acid detection approaches, immunodiagnostics, whole-particle detection, and imaging-based MPXV detection techniques. The insights provided in this article will help researchers to develop novel techniques for the diagnosis of MPXV.

Published in Bioengineering

ISSN: 2306-5354 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Technology; Science: Biology (General)
Website: https://www.mdpi.com/journal/bioengineering

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