Changes in supportive care needs over time from diagnosis up to two years after treatment in head and neck cancer patients: A prospective cohort study

Dominique Molenaar; Irma M. Verdonck-de Leeuw; Birgit I. Lissenberg-Witte; Robert P. Takes; Chris H.J. Terhaard; Johannes A. Langendijk; C. René Leemans; Femke Jansen

Oral Oncology Reports (Jun 2023)

Changes in supportive care needs over time from diagnosis up to two years after treatment in head and neck cancer patients: A prospective cohort study

Dominique Molenaar,
Irma M. Verdonck-de Leeuw,
Birgit I. Lissenberg-Witte,
Robert P. Takes,
Chris H.J. Terhaard,
Johannes A. Langendijk,
C. René Leemans,
Femke Jansen

Affiliations

Dominique Molenaar: Cancer Center Amsterdam Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; Department of Otolaryngology-Head and Neck Surgery, AmsterdamUMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands
Irma M. Verdonck-de Leeuw: Cancer Center Amsterdam Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; Department of Otolaryngology-Head and Neck Surgery, AmsterdamUMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands; Department of Clinical, Neuro- and Developmental Psychology, Faculty of Behavioral and Movement Sciences & Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Van der Boechorststraat 7, 1081 BT, Amsterdam, the Netherlands
Birgit I. Lissenberg-Witte: Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Epidemiology and Data Science, Amsterdam, the Netherlands
Robert P. Takes: Department of Otorhinolaryngology and Head and Neck Surgery, Radboud University Medical Center, Nijmegen, the Netherlands
Chris H.J. Terhaard: Department of Radiotherapy, University Medical Center Utrecht, Utrecht, the Netherlands
Johannes A. Langendijk: Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
C. René Leemans: Cancer Center Amsterdam Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; Department of Otolaryngology-Head and Neck Surgery, AmsterdamUMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands
Femke Jansen: Cancer Center Amsterdam Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; Department of Otolaryngology-Head and Neck Surgery, AmsterdamUMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands; Corresponding author. Amsterdam UMC, Location VU University Medical Center, Department of Otolaryngology-Head & Neck Surgery, P.O. Box 7057, 1007 MB, Amsterdam, the Netherlands.

Journal volume & issue: Vol. 6
p. 100047

Abstract

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Objectives: To investigate changes in supportive care needs (SCNs) over time from diagnosis up to 2 years after treatment among head and neck cancer (HNC) patients, in relation to demographic, personal, clinical, psychological, physical, social, lifestyle, and cancer-related quality of life factors. Materials and methods: Data of the longitudinal NETherlands QUality of Life and Biomedical Cohort study (NET-QUBIC) was used. SCNs were measured using the Supportive Care Needs Survey (SCNS-SF34) and HNC-specific module (SCNS–HNC) before treatment, three, six, 12 and 24 months after treatment. Linear mixed model analyses were used to study SCNs on the physical & daily living (PDL), psychological (PSY), sexuality (SEX), health system, information and patient support (HSIPS), HNC-functioning (HNC-Function), and lifestyle (HNC-Lifestyle) domain, in relation to demographic, personal, clinical, psychological, physical, social, lifestyle, and cancer-related symptoms as measured at baseline. Results: In total, 563 patients were included. SCNs changed significantly over time. At baseline, 65% had ≥1 moderate/high SCN, versus 42.8% at 24 months. Changes in PDL needs were associated with gender, tumor location, smoking, fear of cancer recurrence, oral pain, and appetite loss, changes in PSY with tumor location, fear of recurrence, social support, emotional functioning, physical functioning, coughing, and use of painkillers, changes in SEX with treatment, changes in HSIPS with muscle strength, changes in HNC-Function with tumor stage, location, social support, physical functioning, fatigue, nausea and vomiting, and speech problems, and changes in HNC-Lifestyle with smoking and alcohol use. Conclusion: SCNs diminish over time, but remain prevalent in HNC patients.

Published in Oral Oncology Reports

ISSN: 2772-9060 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.sciencedirect.com/journal/oral-oncology-reports

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