Neurological Research and Practice (Jan 2022)

The special role of CXCL13 in Lyme neuroborreliosis: a case report

  • Deborah K. Erhart,
  • Vera Bracknies,
  • Susanne Lutz-Schuhbauer,
  • Sonja Wigand,
  • Hayrettin Tumani

DOI
https://doi.org/10.1186/s42466-022-00167-y
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 4

Abstract

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Abstract The diagnosis of chronic lyme neuroborreliosis can be a challenge even for experienced neurologists. The clinical picture may be multifaceted, including polyradiculitis to cranial nerve palsies, meningitis, encephalomyelitis, encephalopathy and peripheral neuropathy. We report on a patient presenting with basal leptomeningoencephalitis associated with vasculopathy where the chemokine CXCL13 in cerebrospinal fluid played an important diagnostic role.

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