Journal of Personalized Medicine (May 2024)

Prediction of Failure to Progress after Labor Induction: A Multivariable Model Using Pelvic Ultrasound and Clinical Data

  • Blanca Novillo-Del Álamo,
  • Alicia Martínez-Varea,
  • Elena Satorres-Pérez,
  • Mar Nieto-Tous,
  • Fernando Modrego-Pardo,
  • Carmen Padilla-Prieto,
  • María Victoria García-Florenciano,
  • Silvia Bello-Martínez de Velasco,
  • José Morales-Roselló

DOI
https://doi.org/10.3390/jpm14050502
Journal volume & issue
Vol. 14, no. 5
p. 502

Abstract

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Objective: Labor induction is one of the leading causes of obstetric admission. This study aimed to create a simple model for predicting failure to progress after labor induction using pelvic ultrasound and clinical data. Material and Methods: A group of 387 singleton pregnant women at term with unruptured amniotic membranes admitted for labor induction were included in an observational prospective study. Clinical and ultrasonographic variables were collected at admission prior to the onset of contractions, and labor data were collected after delivery. Multivariable logistic regression analysis was applied to create several models to predict cesarean section due to failure to progress. Afterward, the most accurate and reproducible model was selected according to the lowest Akaike Information Criteria (AIC) with a high area under the curve (AUC). Results: Plausible parameters for explaining failure to progress were initially obtained from univariable analysis. With them, several multivariable analyses were evaluated. Those parameters with the highest reproducibility included maternal age (p p p p p p p Conclusions: A simplified clinical and sonographic model may guide the management of pregnancies undergoing labor induction, favoring individualized patient management.

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