Guoji laonian yixue zazhi (Mar 2024)
Compliance Status and Influencing Factors of Oral Anti-tumor Targeted Drugs inElderly Patients with Colon Cancer after Discharge
Abstract
Objective To analyze the current status of drug compliance and influencing factors of oral anti-tumor targeted drugs in elderly patients with colon cancer after discharge. Methods A total of 110 elderly patients with colon cancer admitted to the First Affiliated Hospital of Harbin Medical University from February 2022 to February 2023 were selected.All patients received oral anti-tumor targeted drug therapy after discharge.Morisky medication compliance questionnaire was used to assess medication compliance, and then the factors affecting medication compliance were statistically analyzed. Results A total of 34 patients had good compliance(good compliance group) and 76 patients had poor compliance (poor compliance group).Univariate analysis showed that the proportion of lack of social support, adverse reactions to oral targeted drug therapy, adverse psychological reactions, poor economic conditions, and lack of knowledge of oral targeted drug therapy in the poor compliance group was significantly higher than that in the good compliance group, and the differences were statistically significant(P<0.05);multivariate logistic regression analysis showed that adverse reactions to oral targeted drug therapy, adverse psychological reactions, poor economic conditions, and lack of knowledge of oral targeted drug therapy were risk factors affecting the compliance of oral targeted drug therapy in elderly patients with colon cancer(P<0.05). Conclusion The medication compliance of oral anti-tumor targeted drugs in elderly patients with colon cancer after discharge is in a moderate stage.Clinical medical staff need to further strengthen the health education for patients in clinical work to improve their awareness of medication, enhance communication with patients and their families to improve negative emotions and psychology, and fundamentally achieve the purpose of improving medication compliance of patients.
Keywords
