Adverse effects of intracardiac dyssynchrony and right ventricular pacing on contractile function and prognosis

Abstract

Pacemaker-induced cardiomyopathy (PICM) is a complication of frequent right ventricular pacing, which in most studies is regarded as a decrease in the left ventricular ejection fraction with constant right ventricular pacing. However, cases of PICM with preserved left ventricular ejection fraction are insufficiently described, since the onset most often occurs as a phenotype of heart failure with preserved ejection fraction. The paper analyzes the studies on the role of constant right ventricular pacing and its contribution to PICM development.

Keywords

• pacemaker-induced cardiomyopathy
• right ventricular pacing
• bradyarrhythmia
• heart failure
• cardiomyopathy
• left ventricular ejection fraction