Genomics & Informatics (Mar 2013)

Eukaryotic DNAJ/K Database: A Comprehensive Phylogenomic Analysis Platform for the DNAJ/K Family

  • Kyeongchae Cheong,
  • Jaehyuk Choi,
  • Jaeyoung Choi,
  • Jongsun Park,
  • Suwang Jang,
  • Yong-Hwan Lee

DOI
https://doi.org/10.5808/GI.2013.11.1.52
Journal volume & issue
Vol. 11, no. 1
pp. 52 – 54

Abstract

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Proteins in DNAJ/K families are ubiquitous, from prokaryotes to eukaryotes, and function as molecular chaperones. For systematic phylogenomics of the DNAJ/K families, we developed the Eukaryotic DNAJ/K Database (EDD). A total of 12,908 DNAJs and 4,886 DNAKs were identified from 339 eukaryotic genomes in the EDD. Kingdom-wide comparison of DNAJ/K families provides new insights on the evolutionary relationship within these families. Empowered by 'class', 'cluster', and 'taxonomy' browsers and the 'favorite' function, the EDD provides a versatile platform for comparative genomic analyses of DNAJ/K families.

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