Chemosensors (Dec 2021)

Recent Progress in the Correlative Structured Illumination Microscopy

  • Meiting Wang,
  • Jiajie Chen,
  • Lei Wang,
  • Xiaomin Zheng,
  • Jie Zhou,
  • Youjun Zeng,
  • Junle Qu,
  • Yonghong Shao,
  • Bruce Zhi Gao

DOI
https://doi.org/10.3390/chemosensors9120364
Journal volume & issue
Vol. 9, no. 12
p. 364

Abstract

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The super-resolution imaging technique of structured illumination microscopy (SIM) enables the mixing of high-frequency information into the optical transmission domain via light-source modulation, thus breaking the optical diffraction limit. Correlative SIM, which combines other techniques with SIM, offers more versatility or higher imaging resolution than traditional SIM. In this review, we first briefly introduce the imaging mechanism and development trends of conventional SIM. Then, the principles and recent developments of correlative SIM techniques are reviewed. Finally, the future development directions of SIM and its correlative microscopies are presented.

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