Cytostatic disease and lipid peroxidation

Abstract

We studied the state of LPO in the animals in experimental radiation sickness and cytostatic (cyclophosphamide and doxorubicin) disease. It is shown that the effect on the body of cytostatic factor activated LPO, increased level of MDA, decreased antioxidant enzyme activity. Last determines the feasibility of control LPO during chemotherapy and radiotherapy and adequate timely correction of lipid peroxidation during their activation.

Keywords

• циклофосфан
• доксорубицин
• лучевая терапия
• перекисное окисление липидов
• МДА
• антиоксидантная активность плазмы