Review of Danshen: From its metabolism to possible mechanisms of its biological activities

B. Mahalakshmi; Chih-Yang Huang; Shin-Da Lee; Nancy Maurya; Rudolf kiefer; V. Bharath Kumar

Journal of Functional Foods (Oct 2021)

Review of Danshen: From its metabolism to possible mechanisms of its biological activities

B. Mahalakshmi,
Chih-Yang Huang,
Shin-Da Lee,
Nancy Maurya,
Rudolf kiefer,
V. Bharath Kumar

Affiliations

B. Mahalakshmi: Department of Research and Development, Vels Publisher, Bodinayakanur, Tamil Nadu, India
Chih-Yang Huang: Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 404, Taiwan; Center of General Education, Buddhist Tzu Chi Medical Foundation, Tzu Chi University of Science and Technology, Hualien 970, Taiwan; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 404, Taiwan
Shin-Da Lee: Department of Physical Therapy, Asia University, Taichung, Taiwan; Department of Physical Therapy, Graduate Institute of Rehabilitation Science, China Medical University, Taichung, Taiwan; Corresponding authors at: Department of Physical Therapy, Asia University, Taichung, Taiwan. Tel.: +886 4 22053366x7300; fax: 886 4 22065051 (S.-D. Lee). Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan. Tel.: +886 4 2332 3456x6352 or 6353; fax: +886 4 23305834 (V. Bharath Kumar).
Nancy Maurya: Department of Botany, Government Science College, Pandhurna, Chhindwara, M.P, India
Rudolf kiefer: Conducting Polymers in Composites and Applications Research Group, Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Vietnam
V. Bharath Kumar: Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan; Corresponding authors at: Department of Physical Therapy, Asia University, Taichung, Taiwan. Tel.: +886 4 22053366x7300; fax: 886 4 22065051 (S.-D. Lee). Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan. Tel.: +886 4 2332 3456x6352 or 6353; fax: +886 4 23305834 (V. Bharath Kumar).

Journal volume & issue: Vol. 85
p. 104613

Abstract

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Danshen (Salvia miltiorrhiza) is a traditional Chinese medicine (TCM) and is frequently used to treat various diseases, such as cardiovascular disease, cancers, liver disease, and nervous system disease. Recent studies have shown that Danshen and its active compounds exhibit prominent protective, anti-inflammatory, antioxidative or antiplatelet properties. The present article reviews the different aspects, such as sources, uses, bioavailability, and medical applications, of Danshen. It is a compilation of all the relevant literature available in this regard in a very concise form to make the readers understand its chemical properties, metabolism, health benefits and other effects. This includes studies that have been done thus far in relation to the therapeutic effects of Danshen in a variety of diseases, such as diabetes, neurological disorders, and even cancer. This article also provides a scientific rationale for understanding the traditional use of Danshen in various diseases.

Published in Journal of Functional Foods

ISSN: 1756-4646 (Print); 2214-9414 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Technology: Home economics: Nutrition. Foods and food supply
Website: https://www.journals.elsevier.com/journal-of-functional-foods

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Abstract

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