THE INFLUENCE OF MULTIFOCAL ATHEROSCLEROSIS ON LONG-TERM OUTCOMES AFTER ENDOVASCULAR REVASCULARIZATION IN MYOCARDIAL INFARCTION

Abstract

Aim. To study the results of primary percutaneous coronary intervention in ST elevation myocardial infarction patients (STE MI) in multivessel disease (MD) according to the multifocal disease (MFA) (peripheral lesion ≥30%).Material and methods. Current study concerns on the evaluation of hemodynamically significant and nonsignificant lesion influence on the prevalence of cardiovascular adverse events in 227 patients during 12 months after primary percutaneous intervention (PCI). The first group consisted of STEMI patients, MD of coronary vessels and MFA, underwent primary PCI (n=63) (STEMI+MFA), second group consisted of patients without MFA (n=164) (STEMI).Results. In STEMI+MFA patients comparing to those without MFA (peripheral arteries lesions more than 30%) there were worse in-hospital and long term outcomes of primary PCI by the prevalence of combined endpoint (death, MI, culprit lesion intervention): 17,4% vs. 6,7% and 30,2% vs. 13,4%, resp. (p <0,05).Conclusion. The prognostic significance of MFA (peripheral arteries lesions more than 30%) after primary PCI in the cohort of patients with STEMI and MD remains underexplored. Current study has shown that presence MFA after primary PCI is a negative prognostic factor in patients with STEMI and MD.

Keywords

• multifocal atherosclerosis
• myocardial infarction with st elevation
• multivessel disease
• primary percutaneous intervention