Nature Communications (Apr 2019)

SWITCH 1/DYAD is a WINGS APART-LIKE antagonist that maintains sister chromatid cohesion in meiosis

  • Chao Yang,
  • Yuki Hamamura,
  • Kostika Sofroni,
  • Franziska Böwer,
  • Sara Christina Stolze,
  • Hirofumi Nakagami,
  • Arp Schnittger

DOI
https://doi.org/10.1038/s41467-019-09759-w
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 15

Abstract

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During cell division, Soronin antagonises WAPL to prevent premature loss of sister chromatid cohesion. Here the authors show that, despite a lack of sequence similarity, the Arabidopsis SWI1 protein functions as a novel Soronin-like WAPL antagonist, suggesting convergent evolution with animals.