Nature Communications (Dec 2017)

Migratory dendritic cells acquire and present lymphatic endothelial cell-archived antigens during lymph node contraction

  • Ross M. Kedl,
  • Robin S. Lindsay,
  • Jeffrey M. Finlon,
  • Erin D. Lucas,
  • Rachel S. Friedman,
  • Beth A. Jirón Tamburini

DOI
https://doi.org/10.1038/s41467-017-02247-z
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 15

Abstract

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Viral infection and vaccination both induce lasting persistence of antigens for protective responses. Here the authors show that migratory dendritic cells, independent of the transcription factor BatF3 for their development, contribute to “archived antigen” exchange with lymphatic endothelial cells.