PLoS ONE (Jan 2013)

Phosphorescent imaging of living cells using a cyclometalated iridium (III) complex.

  • Dik-Lung Ma,
  • Hai-Jing Zhong,
  • Wai-Chung Fu,
  • Daniel Shiu-Hin Chan,
  • Hiu-Yee Kwan,
  • Wang-Fun Fong,
  • Lai-Hon Chung,
  • Chun-Yuen Wong,
  • Chung-Hang Leung

DOI
https://doi.org/10.1371/journal.pone.0055751
Journal volume & issue
Vol. 8, no. 2
p. e55751

Abstract

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A cell permeable cyclometalated iridium(III) complex has been developed as a phosphorescent probe for cell imaging. The iridium(III) solvato complex [Ir(phq)2(H2O]2)] preferentially stains the cytoplasm of both live and dead cells with a bright luminescence.