Frontiers in Genetics (Aug 2020)

A Potential Endurance Algorithm Prediction in the Field of Sports Performance

  • Rocio de la Iglesia,
  • Isabel Espinosa-Salinas,
  • F. Javier Lopez-Silvarrey,
  • F. Javier Lopez-Silvarrey,
  • J. Jose Ramos-Alvarez,
  • J. Carlos Segovia,
  • J. Carlos Segovia,
  • Gonzalo Colmenarejo,
  • Elena Borregon-Rivilla,
  • Helena Marcos-Pasero,
  • Elena Aguilar-Aguilar,
  • Viviana Loria-Kohen,
  • Guillermo Reglero,
  • Guillermo Reglero,
  • Ana Ramirez-de Molina

DOI
https://doi.org/10.3389/fgene.2020.00711
Journal volume & issue
Vol. 11

Abstract

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Sport performance is influenced by several factors, including genetic susceptibility. In the past years, specific single nucleotide polymorphisms have been associated to sport performance; however, these effects should be considered in multivariable prediction systems since they are related to a polygenic inheritance. The aim of this study was to design a genetic endurance prediction score (GES) of endurance performance and analyze its association with anthropometric, nutritional and sport efficiency variables in a cross-sectional study within fifteen male cyclists. A statistically significant positive relationship between GES and the VO2 maximum (P = 0.033), VO2 VT1 (P = 0.049) and VO2 VT2 (P < 0.001) was observed. Moreover, additional remarkable associations between genotype and the anthropometric, nutritional and sport performance variables, were achieved. In addition, an interesting link between the habit of consuming caffeinated beverages and the GES was observed. The outcomes of the present study indicate a potential use of this genetic prediction algorithm in the sports’ field, which may facilitate the finding of genetically talented athletes, improve their training and food habits, as well as help in the improvement of physical conditions of amateurs.

Keywords