Nature Communications (Nov 2017)

Hippocampal GABA enables inhibitory control over unwanted thoughts

  • Taylor W. Schmitz,
  • Marta M. Correia,
  • Catarina S. Ferreira,
  • Andrew P. Prescot,
  • Michael C. Anderson

DOI
https://doi.org/10.1038/s41467-017-00956-z
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 12

Abstract

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It is not fully understood how intrusive or unwanted memories are regulated. Here the authors show that hippocampal GABA concentrations, and coupling between the dorsolateral prefrontal cortex and hippocampus, predict how well subjects can suppress unwanted memories when presented with a reminder.