Two Needle Passes Achieve Similar Diagnostic Yield Compared to Three Passes Regarding Diagnosis of Solid Pancreatic Lesions in Endoscopic Ultrasound-Guided Fine Needle Aspiration

Eleni Koukoulioti; Georgios Tziatzios; Mario Tadic; Stavros Dimitriadis; Paraskevas Gkolfakis; Ekaterini Politi; Tajana Stoos-Veic; Petra Turcic; Alexandros Chatzidakis; Lazaros-Dimitrios Lazaridis; Maria Farmaki; Antonios Vezakis; Konstantinos Triantafyllou; Andreas Polydorou; Ioannis S. Papanikolaou

doi:10.3390/diagnostics11122272

Diagnostics (Dec 2021)

Two Needle Passes Achieve Similar Diagnostic Yield Compared to Three Passes Regarding Diagnosis of Solid Pancreatic Lesions in Endoscopic Ultrasound-Guided Fine Needle Aspiration

Eleni Koukoulioti,
Georgios Tziatzios,
Mario Tadic,
Stavros Dimitriadis,
Paraskevas Gkolfakis,
Ekaterini Politi,
Tajana Stoos-Veic,
Petra Turcic,
Alexandros Chatzidakis,
Lazaros-Dimitrios Lazaridis,
Maria Farmaki,
Antonios Vezakis,
Konstantinos Triantafyllou,
Andreas Polydorou,
Ioannis S. Papanikolaou

Affiliations

Eleni Koukoulioti: Hepatogastroenterology Unit, Second Department of Internal Medicine–Propaedeutic, Research Institute and Diabetes Center, Medical School, National and Kapodistrian University of Athens, ‘‘Attikon” University General Hospital, 12462 Athens, Greece
Georgios Tziatzios: Hepatogastroenterology Unit, Second Department of Internal Medicine–Propaedeutic, Research Institute and Diabetes Center, Medical School, National and Kapodistrian University of Athens, ‘‘Attikon” University General Hospital, 12462 Athens, Greece
Mario Tadic: Endoscopy Unit, Department of Gastroenterology, Hepatology and Clinical Nutrition, Dubrava University Hospital, 10000 Zagreb, Croatia
Stavros Dimitriadis: Hepatogastroenterology Unit, Second Department of Internal Medicine–Propaedeutic, Research Institute and Diabetes Center, Medical School, National and Kapodistrian University of Athens, ‘‘Attikon” University General Hospital, 12462 Athens, Greece
Paraskevas Gkolfakis: Department of Gastroenterology, Hepatopancreatology and Digestive Oncology, Erasme University Hospital, Université Libre de Bruxelles, 1070 Brussels, Belgium
Ekaterini Politi: Department of Cytopathology, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece
Tajana Stoos-Veic: Endoscopy Unit, Department of Gastroenterology, Hepatology and Clinical Nutrition, Dubrava University Hospital, 10000 Zagreb, Croatia
Petra Turcic: Department of Pharmacology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Domagojeva 2, 10000 Zagreb, Croatia
Alexandros Chatzidakis: Hepatogastroenterology Unit, Second Department of Internal Medicine–Propaedeutic, Research Institute and Diabetes Center, Medical School, National and Kapodistrian University of Athens, ‘‘Attikon” University General Hospital, 12462 Athens, Greece
Lazaros-Dimitrios Lazaridis: Hepatogastroenterology Unit, Second Department of Internal Medicine–Propaedeutic, Research Institute and Diabetes Center, Medical School, National and Kapodistrian University of Athens, ‘‘Attikon” University General Hospital, 12462 Athens, Greece
Maria Farmaki: 2nd Department of Surgery, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece
Antonios Vezakis: 2nd Department of Surgery, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece
Konstantinos Triantafyllou: Hepatogastroenterology Unit, Second Department of Internal Medicine–Propaedeutic, Research Institute and Diabetes Center, Medical School, National and Kapodistrian University of Athens, ‘‘Attikon” University General Hospital, 12462 Athens, Greece
Andreas Polydorou: 2nd Department of Surgery, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece
Ioannis S. Papanikolaou: Hepatogastroenterology Unit, Second Department of Internal Medicine–Propaedeutic, Research Institute and Diabetes Center, Medical School, National and Kapodistrian University of Athens, ‘‘Attikon” University General Hospital, 12462 Athens, Greece

DOI: https://doi.org/10.3390/diagnostics11122272
Journal volume & issue: Vol. 11, no. 12
p. 2272

Abstract

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Current guidelines advocate 3–4 passes with a fine-needle aspiration (FNA) to achieve high rates of diagnostic samples for malignancy when performing endoscopic ultrasound (EUS)-guided sampling of solid pancreatic lesions, in the absence of on-site cytologic evaluation. The aim of this study is to compare 2 vs. 3 needle passes in EUS-FNA for solid pancreatic lesions in terms of incremental diagnostic yield and to identify factors associated with the procedure’s outcome. In this retrospective study, 2 passes of EUS-FNA were found to have similar diagnostic yield compared to 3 passes for the diagnosis of solid pancreatic masses, suggesting that there might be no significant incremental tissue yield when 3 passes are performed.

Published in Diagnostics

ISSN: 2075-4418 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: http://www.mdpi.com/journal/diagnostics

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