Nature Communications (Jun 2022)

Forest Fire Clustering for single-cell sequencing combines iterative label propagation with parallelized Monte Carlo simulations

  • Zhanlin Chen,
  • Jeremy Goldwasser,
  • Philip Tuckman,
  • Jason Liu,
  • Jing Zhang,
  • Mark Gerstein

DOI
https://doi.org/10.1038/s41467-022-31107-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 13

Abstract

Read online

In the era of single-cell sequencing, there is a growing need to extract insights from data with clustering methods. Here, inspired by forest fire dynamics, the authors devise an algorithm that can cluster single-cell data with minimal prior assumptions and can compute a non-parametric posterior probability for each data point.