Practical and stereoselective electrocatalytic 1,2-diamination of alkenes

Chen-Yan Cai; Xiao-Min Shu; Hai-Chao Xu

doi:10.1038/s41467-019-13024-5

Nature Communications (Oct 2019)

Practical and stereoselective electrocatalytic 1,2-diamination of alkenes

Chen-Yan Cai,
Xiao-Min Shu,
Hai-Chao Xu

Affiliations

Chen-Yan Cai: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovation Center of Chemistry for Energy Materials, Key Laboratory of Chemical Biology of Fujian Province, and College of Chemistry and Chemical Engineering, Xiamen University
Xiao-Min Shu: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovation Center of Chemistry for Energy Materials, Key Laboratory of Chemical Biology of Fujian Province, and College of Chemistry and Chemical Engineering, Xiamen University
Hai-Chao Xu: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovation Center of Chemistry for Energy Materials, Key Laboratory of Chemical Biology of Fujian Province, and College of Chemistry and Chemical Engineering, Xiamen University

DOI: https://doi.org/10.1038/s41467-019-13024-5
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 7

Abstract

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Methods to prepare 1,2-diamines are desirable due the importance of these compounds as drug scaffolds and organic ligands for metals. Here, the authors report an electrochemical metal-free 1,2- diamination of aryl alkenes with sulfamides to 1,2-diamines with excellent diastereoselectivity.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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