Synthesis and Biological Activities of Aplyronine A Analogues toward the Development of Antitumor Protein–Protein Interaction Inducers between Actin and Tubulin: Conjugation of the C1–C9 Macrolactone Part and the C24–C34 Side Chain

• Kentaro Futaki,
• Momoko Takahashi,
• Kenta Tanabe,
• Akari Fujieda,
• Hideo Kigoshi,
• Masaki Kita

Affiliations

Kentaro Futaki

Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Japan

Momoko Takahashi

Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Japan

Kenta Tanabe

Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Japan

Akari Fujieda

Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan

Hideo Kigoshi

Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Japan

Masaki Kita

Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Japan