Insomnia due to hypnotic abuse

Abstract

Insomnia due to hypnotics abuse and dependence is a common and serious problem of somnology irrespectively of which one comes first: sleep disturbances or drug use. Modern hypnotics demonstrates selective affinity to some types of benzodiazepine receptors. This explains its higher safety profile than for first-generation hypnotics. Nevertheless there are reports of dependence and withdrawal syndrome associated with its administration as well. The most dangerous symptoms of withdrawal are seizures, hemodynamic and respiratory disturbances. Treatment of a hypnotic dependence includes detoxication and gradual withdrawal of medicines.

Keywords

• инсомния
• бензодиазепины
• синдром отмены
• лекарственная толерантность
• insomnia
• hypnotics
• withdrawal syndrome
• abuse