Effects of Hydrofluoroalkane and Dry Powder-Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic Patients

Hans-Peter Hauber; Rame Taha; Celine Bergeron; Vladimir Migounov; Qutayba Hamid; Ron Olivenstein

doi:10.1155/2006/648392

Canadian Respiratory Journal (Jan 2006)

Effects of Hydrofluoroalkane and Dry Powder-Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic Patients

Hans-Peter Hauber,
Rame Taha,
Celine Bergeron,
Vladimir Migounov,
Qutayba Hamid,
Ron Olivenstein

Affiliations

Hans-Peter Hauber: Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada
Rame Taha: Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada
Celine Bergeron: Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada
Vladimir Migounov: 3M Pharmaceuticals, London, Ontario, Canada
Qutayba Hamid: Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada
Ron Olivenstein: Montreal Chest Institute, Montreal, Quebec, Canada

DOI: https://doi.org/10.1155/2006/648392
Journal volume & issue: Vol. 13, no. 2
pp. 73 – 78

Abstract

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BACKGROUND: Inhaled corticosteroids are powerful drugs that can suppress airway inflammation in asthmatic patients. Deposition of most of the inhaled corticosteroid occurs mainly in the central airways. However, a new hydrofluoroalkane formulation of beclomethasone dipropionate (HFA-BDP) is preferentially deposited in the distal airways. Inflammatory characteristics of induced sputum have been shown to differ in samples collected early after sputum induction compared with later.

Published in Canadian Respiratory Journal

ISSN: 1198-2241 (Print); 1916-7245 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: https://onlinelibrary.wiley.com/journal/7503

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