脑小血管病与颅内大动脉病变关系的研究进展 Advance in Relationship between Cerebral Small Vessel Disease and Intracranial Large Artery Disease

Abstract

脑大、小血管在结构和功能上密切相关。越来越多的证据表明脑小血管病常与颅内大动 脉病变共存，严重程度具有一定相关性。颅内大动脉粥样硬化、颅内动脉延长扩张和颅内动脉僵硬 度增加分别反映了颅内大血管的结构和功能改变。本文就脑小血管病与不同颅内大动脉病理变化之 间共存及互相影响的研究现状进行综述，以探讨脑大、小血管病的关系。 Abstract: Cerebral small vessels and large arteries are closely related in structure and function. There is increasing evidence that cerebral small vessel disease often coexists with intracranial large artery disease, and their severity is consistent. Intracranial large artery atherosclerosis, intracranial arterial dolichoectasia and increased arterial stiffness all reflect structural and functional changes of large artery. This article reviewed the research status on the interaction and coexistence between cerebral small vessel disease and intracranial large artery disease.

Keywords

• 脑小血管病
• 脑白质高信号
• 颅内大动脉粥样硬化
• 颅内动脉延长扩张
• 动脉僵硬度
• cerebral small vessel disease
• white matter hyperintensity
• intracranial large artery atherosclerosis
• intracranial arterial dolichoectasia
• arterial stiffness