Nature Communications (Feb 2020)

Deep tissue space-gated microscopy via acousto-optic interaction

  • Mooseok Jang,
  • Hakseok Ko,
  • Jin Hee Hong,
  • Won Kyu Lee,
  • Jae-Seung Lee,
  • Wonshik Choi

DOI
https://doi.org/10.1038/s41467-020-14514-7
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

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In ideal diffraction-limited optical microscopy imaging depth is limited by the multiply scattered wave. Here, the authors present a space gating method, based on an acoustic focus in the object plane and reconstruction using only the acousto-optically modulated ballistic wave, and demonstrate increased imaging depth in scattering samples.