mSystems
(Aug 2021)
A Combination of Metagenomic and Cultivation Approaches Reveals Hypermutator Phenotypes within Vibrio cholerae-Infected Patients
Inès Levade,
Ashraful I. Khan,
Fahima Chowdhury,
Stephen B. Calderwood,
Edward T. Ryan,
Jason B. Harris,
Regina C. LaRocque,
Taufiqur R. Bhuiyan,
Firdausi Qadri,
Ana A. Weil,
B. Jesse Shapiro
Affiliations
Inès Levade
Department of Biological Sciences, University of Montreal, Montreal, Quebec, Canada
Ashraful I. Khan
Center for Vaccine Sciences, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
Fahima Chowdhury
Center for Vaccine Sciences, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
Stephen B. Calderwood
Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
Edward T. Ryan
Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
Jason B. Harris
Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
Regina C. LaRocque
Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
Taufiqur R. Bhuiyan
ORCiD Center for Vaccine Sciences, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
Firdausi Qadri
Center for Vaccine Sciences, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
Ana A. Weil
Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, USA
B. Jesse Shapiro
ORCiD Department of Biological Sciences, University of Montreal, Montreal, Quebec, Canada
DOI
https://doi.org/10.1128/mSystems.00889-21
Journal volume & issue
Vol. 6,
no. 4
Abstract
Read online
Pathogen evolution within patients can impact phenotypes such as drug resistance and virulence, potentially affecting clinical outcomes. V. choleraeV. cholerae
WeChat QR code
Close
