Binucleation ramps up gene expression meeting the physiological demands of an organism

Abstract

In this issue of PLOS Biology, van Rijnberk and colleagues show how polyploidy, via binucleation, enables Caenorhabditis elegans intestinal cells to ramp up gene expression supplying the oocytes with the necessary lipids for optimal organismal growth and reproductive fitness. This Primer explores the implications of a new PLOS Biology study that shows how polyploidy, via binucleation, enables Caenorhabditis elegans intestinal cells to ramp up gene expression, supplying oocytes with the necessary lipids for optimal organismal growth and reproductive fitness.