Nature Communications (Aug 2020)

Geometric principles underlying the proliferation of a model cell system

  • Ling Juan Wu,
  • Seoungjun Lee,
  • Sungshic Park,
  • Lucy E. Eland,
  • Anil Wipat,
  • Séamus Holden,
  • Jeff Errington

DOI
https://doi.org/10.1038/s41467-020-17988-7
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 13

Abstract

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Bacteria can form wall-deficient variants, or L-forms, that divide by a simple mechanism that does not require the FtsZ-based cell division machinery. Here, Wu et al. study L-forms in microfluidic systems to show the importance of geometric effects for cell growth, chromosome segregation and cell division.