A Review on Marvel Fruit: <i>Annona muricata</i>

Abstract

The purpose of this review is to delve into the essence of Annona muricata Linn. A. muricata, also known as soursop, guanabana, and graviola, is a member of the Annonaceae family and has a long history of traditional uses. This is an evergreen plant that grows in the tropical and subtropical regions of the world, primarily in Africa, South America, and Southeast Asia. The medicinal properties of the A. muricata plant are a blessing for humanity, and it has been widely used in folk medicine. A. muricata preparations on the market include candies, syrups, beverages, ice creams, and shakes. Several studies have concluded that the plant contains over 212 chemical constituents such as acetogenins, alkaloids, and phenols. The plant has antibacterial, antiviral, antifungal, antitumor, anthelminthic, analgesic, antiarthritic, hypotensive, anti-inflammatory, and immune-enhancing effects, as well as anti-diabetic activity. Although some toxicities have been reported, the extract of A. muricata has been found to be effective and safe. This review attempts to bring together the majority of the available information on A. muricata’s phytochemistry, traditional uses, biological activities, and toxicity.

Keywords

• <i>Annona muricata</i>
• Annonaceae
• annonaceous acetogenins
• cytotoxicity
• neurotoxicity