Nature Communications (Nov 2017)
Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system
Abstract
The transplantation of tissue-specific progenitor cells may be an approach in organ regeneration. Here the authors show that the nephron progenitor population of a developing mouse kidney, when ablated, can be replaced by exogenously supplied rat nephron progenitors, generating interspecies nephrons.
