Communications Medicine (Jan 2023)

Plasma from patients with pulmonary embolism show aggregates that reduce after anticoagulation

  • Stephen R. Baker,
  • Georgia Halliday,
  • Michal Ząbczyk,
  • Ghadir Alkarithi,
  • Fraser L. Macrae,
  • Anetta Undas,
  • Beverley J. Hunt,
  • Robert A. S. Ariëns

DOI
https://doi.org/10.1038/s43856-023-00242-8
Journal volume & issue
Vol. 3, no. 1
pp. 1 – 5

Abstract

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Baker et al. report the presence of aggregates, possibly composed of amyloid fibrin or other plasma proteins, in blood plasma from patients with acute pulmonary embolism. These aggregates are reduced after treatment with low molecular weight heparin and are similar to those recently identified in the plasma of patients with COVID-19 or long COVID.