Data in support of Gallium (Ga3+) antibacterial activities to counteract E. coli and S. epidermidis biofilm formation onto pro-osteointegrative titanium surfaces
A. Cochis,
B. Azzimonti,
R. Sorrentino,
C. Della Valle,
E. De Giglio,
N. Bloise,
L. Visai,
G. Bruni,
S. Cometa,
D. Pezzoli,
G. Candiani,
L. Rimondini,
R. Chiesa
Affiliations
A. Cochis
Department of Health Sciences, Medical School, University of Piemonte Orientale (UPO), Via Solaroli 17, 28100 Novara, Italy; Department of Biomedical, Surgical and Dental Sciences, Università di Milano/ University of Milan, via Beldiletto 1, 20142 Milan, Italy
B. Azzimonti
Department of Health Sciences, Medical School, University of Piemonte Orientale (UPO), Via Solaroli 17, 28100 Novara, Italy; Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali (INSTM), Via Giusti 9, Local Unit Piemonte Orientale, 50121 Firenze, Italy
R. Sorrentino
Department of Health Sciences, Medical School, University of Piemonte Orientale (UPO), Via Solaroli 17, 28100 Novara, Italy; Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali (INSTM), Via Giusti 9, Local Unit Piemonte Orientale, 50121 Firenze, Italy
C. Della Valle
Department of Chemistry, Materials and Chemical Engineering ‘G.Natta’, Politecnico di Milano, Via Mancinelli 7, 20131 Milano, Italy
E. De Giglio
Department of Chemistry, University of Bari “Aldo Moro”, Via E. Orabona 4, 70126 Bari, Italy
N. Bloise
Molecular Medicine Department, Center for Health Technologies (CHT), UdR INSTM, University of Pavia, Viale Taramelli 3/b, 27100 Pavia, Italy
L. Visai
Molecular Medicine Department, Center for Health Technologies (CHT), UdR INSTM, University of Pavia, Viale Taramelli 3/b, 27100 Pavia, Italy; Department of Occupational Medicine, Toxicology and Environmental Risks, Laboratory of Nanotechnology, Salvatore Maugeri Foundation, IRCCS, Via Boezio 28, 27100 Pavia, Italy
G. Bruni
Department of Chemistry - Physical-Chemistry Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy
S. Cometa
Jaber Innovation s.r.l., Via Calcutta 8, 00100 Roma, Italy
D. Pezzoli
Department of Chemistry, Materials and Chemical Engineering ‘G.Natta’, Politecnico di Milano, Via Mancinelli 7, 20131 Milano, Italy
G. Candiani
Department of Chemistry, Materials and Chemical Engineering ‘G.Natta’, Politecnico di Milano, Via Mancinelli 7, 20131 Milano, Italy
L. Rimondini
Department of Health Sciences, Medical School, University of Piemonte Orientale (UPO), Via Solaroli 17, 28100 Novara, Italy; Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali (INSTM), Via Giusti 9, Local Unit Piemonte Orientale, 50121 Firenze, Italy; Corresponding author at: University of Piemonte Orientale (UPO), Department of Health Sciences, Via Solaroli 17, 28100 Novara, Italy. Tel.: +39 0321 660673; fax: +39 0321 620421.
R. Chiesa
Department of Chemistry, Materials and Chemical Engineering ‘G.Natta’, Politecnico di Milano, Via Mancinelli 7, 20131 Milano, Italy
This paper contains original data supporting the antibacterial activities of Gallium (Ga3+)-doped pro-osteointegrative titanium alloys, obtained via Anodic Spark Deposition (ASD), as described in “The effect of silver or gallium doped titanium against the multidrug resistant Acinetobacter baumannii” (Cochis et al. 2016) [1].In this article we included an indirect cytocompatibility evaluation towards Saos2 human osteoblasts and extended the microbial evaluation of the Ga3+ enriched titanium surfaces against the biofilm former Escherichia coli and Staphylococcus epidermidis strains. Cell viability was assayed by the Alamar Blue test, while bacterial viability was evaluated by the metabolic colorimetric 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay. Finally biofilm morphology was analyzed by Scanning Electron Microscopy (SEM). Data regarding Ga3+ activity were compared to Silver. Keywords: E. coli, S. epidermidis, Biofilm, Gallium, Silver, Titanium, Anodic Spark Deposition
