862 Targeting PSGL-1, a novel macrophage checkpoint, repolarizes suppressive macrophages, induces an inflammatory tumor microenvironment, and suppresses tumor growth

• Phuong Nguyen,
• Igor Feldman,
• Mohammad Zafari,
• Ryan Phennicie,
• Kevin Kauffman,
• Dominika Nowakowska,
• Veronica Komoroski,
• Steve Sazinsky,
• Joe Wahle,
• Denise Manfra,
• Shantashri Vaidya,
• Michael Brehm,
• Tatiana Novobrantseva

Affiliations

Phuong Nguyen

Aff147 grid.39382.33000000012160926XBaylor College of Medicine, Center for Cell and Gene Therapy Houston TX USA

Igor Feldman

Aff1 Jounce Therapeutics Cambridge MA USA

Mohammad Zafari

Aff1 Jounce Therapeutics Cambridge MA USA

Ryan Phennicie

1Verseau Therapeutics, Bedford, MA, USA

Kevin Kauffman

1Verseau Therapeutics, Bedford, MA, USA

Dominika Nowakowska

1Verseau Therapeutics, Bedford, MA, USA

Veronica Komoroski

1Verseau Therapeutics, Bedford, MA, USA

Steve Sazinsky

1Verseau Therapeutics, Bedford, MA, USA

Joe Wahle

1Verseau Therapeutics, Bedford, MA, USA

Denise Manfra

1Verseau Therapeutics, Bedford, MA, USA

Shantashri Vaidya

2UMass Medical School, Worcester, MA, USA

Michael Brehm

2UMass Medical School, Worcester, MA, USA

Tatiana Novobrantseva

1Verseau Therapeutics, Bedford, MA, USA