Neurotropic action of soy lecithin in the process of cognitive function formation in white rats.

Abstract

In experiments conducted on white rats neurotropic action of soy lecithin, known as a source of unsaturated fatty acids on the background of the neurotoxic impact of CCl4was studied. Useage of CCl4by courses showed a significant inhibitory effect that affected the spontaneous behavior of rats “in the open field” by significant inhibition of mobility (44 - 77%), research activity (81%) and increased emotionality (140%). Suchusageofsoy lecithin having anti-oxidant activity and membrane-stabilizing effect led to optimization of spontaneous behavior of rats. Theinfringement of cognitive function is, possibly, due to the prooxydative effect ofCCl4 anddecreaseintheunsaturated fatty acid fraction in the structure of the brain lipids.Level of research, mink instinct, emotionality, vertical mobility were restored, and horizontal mobility even increased by 59%. Thus, soy lecithin may be recommended as a drug with correcting cognitive brain function.

Keywords

• soy lecithin
• polyunsaturated fatty acids (PUFAs)
• cognitive function