Myosin 1b is an actin depolymerase

Julien Pernier; Remy Kusters; Hugo Bousquet; Thibaut Lagny; Antoine Morchain; Jean-François Joanny; Patricia Bassereau; Evelyne Coudrier

doi:10.1038/s41467-019-13160-y

Nature Communications (Nov 2019)

Myosin 1b is an actin depolymerase

Julien Pernier,
Remy Kusters,
Hugo Bousquet,
Thibaut Lagny,
Antoine Morchain,
Jean-François Joanny,
Patricia Bassereau,
Evelyne Coudrier

Affiliations

Julien Pernier: Laboratoire Physico-Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168
Remy Kusters: Laboratoire Physico-Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168
Hugo Bousquet: Sorbonne Université
Thibaut Lagny: Laboratoire Physico-Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168
Antoine Morchain: Laboratoire Physico-Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168
Jean-François Joanny: Laboratoire Physico-Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168
Patricia Bassereau: Laboratoire Physico-Chimie Curie, Institut Curie, PSL Research University, CNRS UMR168
Evelyne Coudrier: Sorbonne Université

DOI: https://doi.org/10.1038/s41467-019-13160-y
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 7

Abstract

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Former evidence suggests a correlation between the function of non-conventional myosin motors and actin dynamics. Here authors use in vitro assays in which they observe that actin sliding on myosin 1b immobilized or bound to a fluid bilayer enhances actin depolymerization at the barbed end.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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