RESEARCH PROGRESS IN INDIVIDUALIZED DRUG SCREENING TECHNOLOGY FOR PATIENTS WITH TUMORS

Abstract

In China, the incidence of tumors is increasing year by year, with the number of patients with new tumors ranking first in the world. Currently, tumors are usually treated with surgery combined with radiotherapy, chemotherapy, targeted therapy, or immunotherapy. However, individuals with tumors vary substantially in response to chemotherapeutic drugs. Therefore, selecting the drugs that patients are most sensitive to through the in vitro drug sensitivity screening technology is of great importance to guide personalized drug treatment of patients with tumors. Currently, there are various techniques for personalized anti-tumor drug screening, each with its own advantages and disadvantages. This article reviews the application progress on several commonly used techniques, with the aim to provide a reference for the selection of personalized anti-tumor drug screening techno-logy.

Keywords

• neoplasms|drug screening assays, antitumor|genome aequencing|organoids|xenograft model antitumor assays|precision medicine|disease models, animal|review