Synthetic Strategies to Terpene Quinones/Hydroquinones

Abstract

The cytotoxic and antiproliferative properties of many natural sesquiterpene-quinones and -hydroquinones from sponges offer promising opportunities for the development of new drugs. A review dealing with different strategies for obtaining bioactive terpenyl quinones/hydroquinones is presented. The different synthetic approches for the preparation of the most relevant quinones/hydroquinones are described.

Keywords

• terpene quinone
• terpene hydroquinone
• synthesis
• chemical modification