Panhypopituitarism Secondary to Pituitary Macroadenoma

Abstract

Pituitary adenomas represent 10 % of central nervous system tumors and have a prevalence of 80 cases/100 000 people. The compression they cause on adjacent structures is responsible for anterior pituitary hormone secretion disorders. The case of secondary panhypopituitarism to a pituitary macroadenoma in a patient treated at the Dr. Gustavo Aldereguía Lima University General Hospital in Cienfuegos is presented. This is a 52-years-old male patient with white skin color who came in for fainting and behavioral changes. On physical examination, he presented absence of thoraco-abdominal and pubic hair, hypotension, and temporal-spatial disorientation. Paraclinical studies showed severe hyponatremia with low osmolarity. Endocrine function evidenced panhypopituitarism. Magnetic resonance imaging revealed a 17-mm lesion in the sella turcica suggestive of a pituitary macroadenoma. The patient is being monitored by the Medicine and Endocrinology Services with cortisone replacement treatment and is awaiting surgical treatment.

Keywords

• adenohipófisis
• hormonas adenohipofisarias
• hipopituitarismo
• neoplasias hipofisarias