Clinical efficiency of a new allograft cervical cage in treatment of cervical spondylosis

Abstract

Objective To evaluate the efficacy and reliability of a novel allograft cervical cage in treatment of cervical spondylosis, and observe the effect of subsidence on clinical outcome. Methods We retrospectively reviewed 80 cases with cervical spondylosis undergoing anterior cervical discectomy and fusion (ACDF) with BioCage® or PEEK cage in our department from January 2015 to December 2016. During follow-up, X-ray film (anterior-posterior and lateral) and computed tomography (CT) scan were used to assess segmental and overall cervical lordosis, intervertebral height, cage positioning, and final fusion state. Visual analog scale (VAS) and neck disability index (NDI) were calculated to evaluate clinical outcomes. Results There were 43 cases (29 males and 14 females, at a mean age of 50.44 years, ranging from 24 to 81) undergoing ACDF using Biocage® and 37 cases (26 males and 11 females, at a mean age of 49.31 years, ranging from 24 to 78) using PEEK cage. During the follow-up of 12 to 36 months (average 23.02 months), the segmental and overall cervical lordosis were greatly improved in both groups (P 0.05). Conclusion The novel cervical allograft cage (BioCage®) is designed according to the anatomical shape of Chinese cervical vertebra. Its large bone contact area of endplate and dentate processes on surface can effectively prevent the slip of the cage and provide immediate postoperative stability. At the same time, the cage facilitates the normal cervical lordosis, and has a good safety and effective adjunct to ACDF for the treatment of patients with cervical spondylosis.

Keywords

• anterior cervical discectomy and fusion
• allograft bone
• cage
• peek
• spine fusion
• subsidence