Nanoengineering facilitating the target mission: targeted extracellular vesicles delivery systems design

Abstract

Highlights 1. Tracing the full range of factors affecting EVs targeting mission in terms of EV components, cell sources, and delivery methods. 2. Strategies for EVs surface display and post-isolation methods facilitate the targeted delivery efficiency of the loading therapeutic cargo. 3. EVs complemented by non-invasive strategies such as magnetic fields, ultrasound, and photothermal further enhance targeting efficacy.

Keywords

• Extracellular vesicles
• Drug delivery
• Targeting
• Nanoengineering EVs
• Biodistribution