Romanian Journal of Pediatrics (Jun 2017)

MEDULLOBLASTOMA – CLINICAL AND THERAPEUTICAL ASPECTS

  • Catalin Prazaru,
  • Georgeta Diaconu,
  • Ana Ulinici,
  • Abou Ainain,
  • Alexandra Stoicescu Prazaru,
  • Ioana Grigore

DOI
https://doi.org/10.37897/RJP.2017.2.5
Journal volume & issue
Vol. 66, no. 2
pp. 115 – 119

Abstract

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Medulloblastoma is a primitive neuroectodermal tumor commonly seen in pediatric age, with peak incidence between 5 and 10 years. The tumor is generally located in the vermis or cerebellar hemispheres invading IV ventricle. Symptomatology is dominated by signs of intracranial hypertension and cerebellar ataxia. Neuroimaging explorations contributes to diagnosis and more precise staging medulloblastoma. The treatment is complex including surgical resection of the tumor followed by radiotherapy and chemotherapy. The prognosis is generally reserved, incidence of neurological sequelae after treatment is high.

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