Alteration in different lipoprotein fractions in chronic renal failure patients

Abstract

Background: Chronic renal failure, which is an inevitable terminal pathway of any chronic renal parenchymal disease, is more known for its morbidity than for its mortality. Objective: To note the alteration in different lipoprotein fractions among chronic renal failure patients. Methods: 70 Cases of chronic renal failure were taken for study. These patients were divided into two groups of 35 each. One group consisting of 35 Patients who were on conservative treatment, and the other group of 35 patients were on regular short term hemodialysis (6 months – 2 years). Patients were selected from Kasturba Medical College Hospitals and from Wenlock Government Hospital, Mangalore, from April 2001 to December 2003. Results: The HDL – cholesterol level was found to be significantly lower compared to control group. The total cholesterol and LDL was not raised significantly. The HDL/TC ratio was significantly reduced. Conclusion: Significant rise in triglyceride and VLDL concentration was seen in chronic renal failure patients.

Keywords

• lipoprotein fractions
• chronic renal failure
• vldl