Journal of Clinical Medicine (Dec 2022)

Multimodality Imaging Approach to Spontaneous Coronary Artery Dissection

  • Gemma Marrazzo,
  • Stefano Palermi,
  • Fabio Pastore,
  • Massimo Ragni,
  • Mariarosaria De Luca,
  • Michele Gambardella,
  • Gaetano Quaranta,
  • Giancarlo Messalli,
  • Lucia Riegler,
  • Valeria Pergola,
  • Andrea Manto,
  • Antonello D’Andrea

DOI
https://doi.org/10.3390/jcm12010154
Journal volume & issue
Vol. 12, no. 1
p. 154

Abstract

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Spontaneous Coronary Artery Dissection (SCAD) refers to the spontaneous separation of the layers of the vessel wall caused by intramural hemorrhage, with or without an intimal tear. The “typical” SCAD patient is a middle-aged woman with few traditional cardiovascular risk factors, and it’s frequently associated with pregnancy. Because of its low incidence, its pathophysiology is not fully understood. SCAD presents as an acute coronary syndrome, with chest pain, dyspnea, syncope, or heartbeat, even if diagnosis and clinical handling are different: coronary angiography is currently the main tool to diagnose SCAD; however, in doubtful cases, the use of both invasive and noninvasive cardiovascular imaging methods such as intravascular ultrasound or optical coherence tomography may be necessary. This paper aims to review the current state of knowledge on SCAD to address its demographic features, clinical characteristics, management, and outcomes, focusing on diagnostic algorithms and main multimodality imaging techniques.

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