The first case of Escherichia fergusonii with biofilm in China and literature review

Abstract

Abstract Background Escherichia fergusonii is a rare opportunistic pathogen in humans and animals, especially with biofilm. Methods In one case, E. fergusonii with biofilm was detected in the bile, and silver staining was used to prove it had biofilm. The clinical characteristics and drug susceptibility of eight cases of E. fergusonii retrieved from the literature were also summarized. Results This is a case of E. fergusonii with biofilm, which has not been reported in China. The 8 cases retrieved from the literature did not specify whether they had biofilm, but we analyzed their clinical characteristics and drug susceptibility. All patients were treated with antimicrobial drugs. 8 cases showed sensitivity to piperacillin/tazobactam and imipenem in 6 cases (75%), but poor sensitivity to levofloxacin and ciprofloxacin. Conclusion The silver staining method proved biofilm in this case, which is the first case of E. fergusonii with biofilm in China.

Keywords

• Drug resistance
• Escherichia fergusonii
• Infection
• Literature review
• Silver staining