Nature Communications (Nov 2018)
A third generation of radical fluorinating agents based on N-fluoro-N-arylsulfonamides
Abstract
Common radical fluorination reagents, such as Selectofluor®, are penalized by the need for metal catalysts and possible oxidation side reactions. Here, the authors reported the synthesis and application of N-fluoro-N-arylsulfonamides (NFASs) as third generation of radical fluorinating reagents to overcome those limitations.