Characteristics of Visual Evoked Potential in Different Parts of Visual Impairment

DAI Ding-kun; YANG Li; MENG Huan-huan; CHEN Xi-ping; TAO Lu-yang

doi:10.12116/j.issn.1004-5619.2020.201004

Fayixue Zazhi (Oct 2021)

Characteristics of Visual Evoked Potential in Different Parts of Visual Impairment

DAI Ding-kun,
YANG Li,
MENG Huan-huan,
CHEN Xi-ping,
TAO Lu-yang

Affiliations

DAI Ding-kun: Judicial Appraisal Institute of Northern Jiangsu People's Hospital, Yangzhou 225001, Jiangsu Province, China
YANG Li: Department of Forensic Medicine (Institute of Forensic Sciences), Soochow University, Suzhou 215123, China
MENG Huan-huan: Department of Forensic Medicine (Institute of Forensic Sciences), Soochow University, Suzhou 215123, China
CHEN Xi-ping: Department of Forensic Medicine (Institute of Forensic Sciences), Soochow University, Suzhou 215123, China
TAO Lu-yang: Department of Forensic Medicine (Institute of Forensic Sciences), Soochow University, Suzhou 215123, China

DOI: https://doi.org/10.12116/j.issn.1004-5619.2020.201004
Journal volume & issue: Vol. 37, no. 5
pp. 632 – 638

Abstract

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ObjectiveTo study the quantitative and qualitative differences of visual evoked potential （VEP） in monocular visual impairment after different parts of visual pathway injury.MethodsA total of 91 subjects with monocular visual impairment caused by trauma were selected and divided into intraocular refractive media-injury group （eyeball injury group for short）, optic nerve injury group, central nervous system injury and intracranial combined injury group according to the injury cause and anatomical segment. Pattern Reversal visual evoked potential （PR-VEP） P100 peak time and amplitude, Flash visual evoked potential （F-VEP） P2 peak time and amplitude were recorded respectively. SPSS 26.0 software was used to analyze the differences of quantitative （peak time and amplitude） and qualitative indexes （spatial frequency sweep-VEP acuity threshold, and abnormal waveform category and frequency） of the four groups.ResultsCompared with healthy eyes, the PR-VEP P100 waveforms of the intraocular eyeball injury group and the F-VEP P2 waveforms of the optic nerve group showed significant differences in prolonged peak time and decreased amplitude in injured eyes （P<0.05）. The PR-VEP amplitudes of healthy eyes were lower than those of injured eyes at multiple spatial frequencies in central nervous system injury group and intracranial combined injury group （P<0.05）.The amplitude of PR-VEP in patients with visual impairment involving central injury was lower than that in patients with eye injury at multiple spatial frequencies. The frequency of VEP P waveforms reaching the threshold of the intraocular injury group and the optic nerve injury group were siginificantly different from the intracranial combined injury group, respectively（P<0.008 3）, and the frequency of abnormal reduction of VEP amplitude of threshold were significantly different from the central nervous system injury group, respectively（P<0.008 3）.ConclusionVEP can distinguish central injury from peripheral injury, eyeball injury from nerve injury in peripheral injury, but cannot distinguish simple intracranial injury from complex injury, which provides basic data and basis for further research on the location of visual impairment injury.

Published in Fayixue Zazhi

ISSN: 1004-5619 (Print)
Publisher: Editorial Office of Journal of Forensic Medicine
Country of publisher: China
LCC subjects: Medicine
Website: http://www.fyxzz.cn/EN/1004-5619/home.shtml

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