Residues of aflatoxins B1 and M1 in different biological matrices of swine orally administered aflatoxin B1 and Saccharomyces cerevisiae

Abstract

Mycotoxins are acutely toxic, carcinogenic, mutagenic, and oestrogenic secondary metabolites produced by moulds, mostly of the genera Aspergillus, Penicillum and Fusarium. Aflatoxins (AFs) are dangerous molecules to animals and humans produced mostly by Aspergillus flavus and A. parasiticus (Marin et al., 2002). Aflatoxin B1 (AFB1) is the most potent of all aflatoxins and is of great concern because of its adverse effects to the health of humans and domestic animals, including also teratogenic and immunosuppressive effects (Eaton and Callagher, 1994). Aflatoxin M1 (AFM1) is a hydroxilated metabolite of AFB1 characterized by a rapid elimination through the milk and the urine, and by a lower toxicity than its parent compound.

Keywords

• aflatoxins B1 and M1, swine, residues